In Rome, a Virgin Mary statue is found crying blood. Pondering on the implications of the existence of miracles, and eventually, the existence of God, the people involved in the enigma start losing their minds.

A young policewoman slowly goes insane while tracking down an elusive serial rapist/killer through Italy when she herself becomes a victim of the brutal man's obsession.

Samantha, a young kidnapped girl, resurfaces in shock after being imprisoned and hospitalized. Next to her is Dr. Green, a profiler who investigates victims' minds to find clues. Genko, a private investigator, is also on the kidnapper's trail.

The series is about a woman who returns to a mysterious village in Northern Italy where she grew up, only to find her past returning to haunt her and her teenage children.